StraARS 2023
Aminoacyl-tRNA synthetases : sculpting codes and shaping cell physiology
Scientific Program
08:00 Registration
08:30 Welcome coffee & Registration
09:00 Catherine Florentz University of Strasbourg, VP of Strategic Planning and Actions
University Welcome Talk
09:05 CNRS Representative
CNRS Welcome Talk
09:10 Pierre Antony Co-Organizer CNRS UMR 7104 - Inserm U 1258 – IGBMC/University of Strasbourg
Welcome Talk "The raison d’être of StraARS2023"
09:15 Hubert Becker Co-Organizer UMR 7156 GMGM – IPCB/University of Strasbourg
Welcome Talk and Acknowledgements
DAY 1 – May 23rd
Session 1 : Aminoacyl-tRNA Synthetases : code gatekeeper
Session Chair : Ya-Ming Hou
09:20 Dino Moras Plenary lecture CNRS UMR 7104 - Inserm U 1258 – IGBMC/University of Strasbourg
aaRSs and RNA world a tale to be
10:05 Osamu Nureki Tokyo University, Japan
Amino acid transfer from aa-tRNA to lipids modulates immunity
10:30-11:00 Coffee Break
11:00 Rajan Sankaranarayanan CCMB Hyderabad, India
Discriminatory Tales!
11:25 Richard Giegé IBMC/University of Strasbourg
Primordial tRNA identities for aminoacylation and ancillary identities reveal a tRNA code biology
11:50 Juliette Godin IGBMC/University of Strasbourg
The tRNAs journey through cortical development: Where it started, where it goes?
12:15 Gilbert Eriani UPR 9002 – IBMC/University of Strasbourg
A tRNA mimicry strategy to explore ribosome decoding rules
12:40-14:30 Lunch
14:30 Lluis Ribas de Pouplana IRB, Barcelona, Spain
Signal saturation in tRNAs – shutting the gate?
Session 3 : Aminoacyl-tRNA Synthetases and tRNAs design new physiology
Session Chair : Osamu Nureki
14:55 Hiro Suga Tokyo University, Japan
Genetic Code Reprogramming Facilitated by Flexizymes
15:20 Jesse Rinehart Yale University, USA
Large scale synthetic human phosphoproteome to decode novel protein-protein interaction networks
15:45 Dieter Söll Plenary lecture Yale University, USA
Pyrrolysine and Selenocysteine - different designs to manifest the genetic code
16:30-17:00 Coffee Break
Session Chair : Hubert Becker
17:00 Sunghoon Kim Yonsei University & BIOCON, Korea
Multi-tRNA Synthetase Complex for the Control of Cancer Pathways at Systems Level
17:25 Paul Schimmel Plenary lecture Scripps, California, USA
Brave new world of tRNA synthetase regulation of RNA splicing
DAY 2 – May 24th
Session 2 : Aminoacyl-tRNA synthetases shape synthetic genetic codes
Session Chair : Sunghoon Kim
09:00 Ignacio Luque Csic Sevilla, Spain
Aminoacyl-tRNA synthetases and tRNAs in cyanobacteria, a decade of surprises
09:25 Marie Sissler IECB, Bordeaux
Mitochondrial aminoacyl-tRNA synthetases and connections to diseases
09:50 Frédéric Fischer IPCB/University of Strasbourg
Aminoacyl-tRNA-dependent sterol modifications in fungi
10:15 Constantinos Stathopoulos Patras University, Greece
“Unboxing” the diversity of tRNA-mediated aaRS transcription regulation in pathogens
10:40-11:10 Coffee Break
11:10 Magali Frugier UPR 9002 – IBMC/University of Strasbourg
Two aminoacyl-tRNA synthetase complexes, membrane localization and unusual role in tRNA import: many questions remain about tRNA biology in Plasmodium
11:35 Leslie Nangle aTyr Pharma, USA
Developing Novel Therapeutics Based on Aminoacyl-tRNA Synthetases
12:00 Hubert Becker - Co-organizer
Concluding remarks
12:05 Pierre Antony - Co-organizer
Invitation to a musical journey
12:10 Strasbourg University student choir – direction – Amanda Hascher
Georges Bizet – Carmen – Chœur des cigarières
Wolfgang Amadeus Mozart – Cosi fan tutte – Secondate
Jean-Philippe Rameau – Rondeau des Indes galantes
Gaetano Donizetti – La Fille du régiment – Rataplan
Giuseppe Verdi – La Traviata – Chœur des bohémiennes et chœur des matadores
12:35 University of Strasbourg Representative
Conclusion of StraARS2023
12:40-14:30 Lunch
08:30 Welcome coffee
Session 3 : Aminoacyl-tRNA Synthetases and tRNAs design new physiology
