Aminoacyl-tRNA Synthetases (aaRSs) constitute an ancient and ubiquitous family of enzymes essentially known for their primary function of attaching all genetically-encoded amino acids to their cognate transfer RNA (tRNA), thereby producing the full set of aminoacyl-tRNAs used by translating ribosomes for protein synthesis. However, most of the worldwide research community is not aware that, in addition to their role in decoding codons for protein synthesis, these enzymes exert a fascinating myriad of non-canonical and often nontranslational functions. Indeed, they are involved in cytokine production, import of fatty acids, control of inflammation, regulation of the TOR pathway, angiogenesis… Moreover, any tiny dysfunctioning of either their canonical role but also of their nontranslational functions leads to severe diseases among which many forms of cancers and a plethora of neurological disorders, which constitute the main research focus of many researchers world-wide.
This meeting entitled “StraARS 2023 – Aminoacyl-tRNA synthetases : sculpting codes and shaping cell physiology” will concentrate on the three cornerstone facets of tRNA and aminoacyl-tRNA synthetase research:
How they shaped and maintain the genetic code
Their involvement, through nontranslational functions, to signaling and regulatory circuits at the heart of cell physiology and how their dysfunctioning leads to Human diseases and
How we can manipulate aminoacylation systems and engineer new ones to design new genetic codes for synthetic biology.
These topics are perfectly in-line with the research of a wide range of groups and will give them the opportunity to expand knowledge that are potentially valuable for the development of their own research. This meeting constitutes a unique opportunity for researchers to expand knowledge that is potentially valuable for the development of their own research and for students to set up connections with renowned labs for internships and future prospects.
About StraARS 2023
Our Sponsors
Lead Co-organizers
Pr. Hubert D. BECKER (UMR 7156 GMGM – IPCB/University of Strasbourg)
Dr. Pierre ANTONY (CNRS UMR 7104 - Inserm U 1258 – IGBMC)
Organizing Committee:
Dr. Bruno SENGER (UMR 7156 GMGM – IPCB/University of Strasbourg)
Ms. Laurence HUCK (Technician - CNRS)
Dr. Nassira MAHMOUDI (UMR 7156 GMGM – IPCB/University of Strasbourg)
Ms. Solène ZUTTION (UMR 7156 GMGM – IPCB/University of Strasbourg)
Ms. Aline KEILBACH (UMR 7156 GMGM – IPCB/University of Strasbourg)
Scientific and Advisory Board Members
Dr. Dino MORAS (CNRS UMR 7104 - Inserm U 1258 – IGBMC)
Dr. Ali HAMICHE (CNRS UMR 7104 - Inserm U 1258 – IGBMC)
Pr. Catherine FLORENTZ (Vice-Chairperson Strategies & Developments, University of Strasbourg)
Dr. Gilbert ERIANI (UPR 9002 – IBMC)
Dr. Magalie FRUGIER (UPR 9002 – IBMC)
Dr. Philippe GIEGÉ (UPR 2357 – IBMP)
Dr. Marie SISSLER (IPCB/University of Strasbourg)
Pr. Jean CAVARELLI (IGBMC)
Mr. Patrick BARTH (Research Engineer – CNRS)
StraARS 2023 Scientific & Organizing committee
Have questions?
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contact@straars2023.org
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